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Ali1234Researcher

The main reason for the rapid spread of the most common and deadly type of cancer!

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  1. Ali1234 Researcher
    Added an answer on July 3, 2025 at 6:17 am

    Based on current data, lung cancer is generally considered the most common and deadly type of cancer globally, accounting for the highest number of cancer-related deaths. While other cancers like breast, prostate, and colorectal cancer are very common in terms of new cases, lung cancer has a signifiRead more

    Based on current data, lung cancer is generally considered the most common and deadly type of cancer globally, accounting for the highest number of cancer-related deaths. While other cancers like breast, prostate, and colorectal cancer are very common in terms of new cases, lung cancer has a significantly lower survival rate due to its aggressive nature and often late diagnosis.
    The rapid spread (metastasis) of lung cancer, and cancer in general, is primarily due to several interconnected factors:
    * Genetic Mutations and Uncontrolled Cell Growth: Cancer fundamentally arises from genetic mutations within cells that cause them to grow and divide uncontrollably, ignoring the body’s normal regulatory signals. These mutations can be inherited or acquired due to environmental factors.
    * Ability to Invade and Metastasize: Cancer cells gain the ability to detach from the primary tumor, invade surrounding tissues, and enter the bloodstream or lymphatic system. Once in these systems, they can travel to distant parts of the body and form new tumors (metastasis).
    * Late Diagnosis: For many aggressive cancers, including lung cancer, symptoms often don’t appear until the disease has already progressed to an advanced stage and potentially metastasized. This significantly limits treatment options and reduces the chances of a cure.
    * Aggressive Nature of Certain Cancer Types: Some cancer types, like pancreatic cancer and certain lung cancers, are inherently more aggressive, meaning they grow and spread more rapidly than others.
    * Microenvironment and Supporting Factors: The tumor’s microenvironment, including factors like a weakened immune system, lack of oxygen (hypoxia), and other cellular processes, can contribute to the cancer cells’ ability to survive, grow, and spread.
    Specific to Lung Cancer, major contributing factors to its prevalence and rapid spread include:
    * Tobacco Use: Smoking is by far the leading risk factor for lung cancer, accounting for a significant majority of cases. The carcinogens in tobacco smoke directly damage lung cells, leading to mutations.
    * Environmental Factors: Exposure to other carcinogens like radon gas, asbestos, and air pollution also significantly increases the risk of lung cancer.
    In summary, the rapid spread and deadliness of lung cancer (and other aggressive cancers) stem from their inherent biological characteristics—uncontrolled growth, ability to metastasize, and often late detection—coupled with major preventable risk factors, especially tobacco use.

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Ali1234Researcher

Are you worried about joint or back pain?

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Ali1234Researcher

ذیابیطس مریضوں کو تربوز سے اجتناب کیوں کرنا چاہیئے؟

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  1. Ali1234 Researcher
    Added an answer on July 2, 2025 at 11:40 pm

    ذیابیطس کے مریضوں کو تربوز کھانے میں احتیاط برتنی چاہیے کیونکہ اگرچہ یہ ایک صحت مند، پانی سے بھرپور پھل ہے لیکن اس کے اندر موجود قدرتی شکر اور گلائسیمک انڈیکس  ذیابیطس کے مریضوں پر منفی اثر ڈال سکتا ہے۔ تربوز کا گلائسیمک انڈیکس تقریباً 72 ہے جو اسے تیزی سے شوگر بڑھانے والا پھل بناتا ہے۔ زیادہ گلائسیRead more

    ذیابیطس کے مریضوں کو تربوز کھانے میں احتیاط برتنی چاہیے کیونکہ اگرچہ یہ ایک صحت مند، پانی سے بھرپور پھل ہے لیکن اس کے اندر موجود قدرتی شکر اور گلائسیمک انڈیکس  ذیابیطس کے مریضوں پر منفی اثر ڈال سکتا ہے۔

    تربوز کا گلائسیمک انڈیکس تقریباً 72 ہے جو اسے تیزی سے شوگر بڑھانے والا پھل بناتا ہے۔

    زیادہ گلائسیمک انڈیکس والے کھانے خون میں گلوکوز کی سطح کو تیزی سے بڑھاتے ہیں، جو ذیابیطس کے مریضوں کے لیے خطرناک ہو سکتا ہے۔

    دوسری جانب تربوز کا گلائسیمک لوڈ کم ہوتا ہے (تقریباً 5 فی 100 گرام) لیکن اگر زیادہ مقدار میں کھایا جائے تو یہ شوگر لیول پر اثرانداز ہو سکتا ہے۔

    تربوز میں جو قدرتی مٹھاس پائی جاتی ہے، وہ فرکٹوز ہے جو اگر بڑی مقدار میں لیا جائے تو انسولین کے مؤثر عمل کو متاثر کر سکتا ہے۔ خاص طور پر ٹائپ 2 ذیابیطس میں، جسم شوگر کو مؤثر طریقے سے استعمال نہیں کر

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Ali1234Researcher

Cough medicine is useful for asthma patients,

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  1. Ali1234 Researcher
    Added an answer on July 2, 2025 at 11:37 pm

    The statement "Cough medicine is useful for asthma patients" is generally not true and can even be detrimental in many cases. Here's why: Asthma coughs are different: A cough in an asthma patient is usually a symptom of underlying airway inflammation and narrowing, not just a simple irritation likeRead more

    The statement “Cough medicine is useful for asthma patients” is generally not true and can even be detrimental in many cases.

    Here’s why:

    • Asthma coughs are different: A cough in an asthma patient is usually a symptom of underlying airway inflammation and narrowing, not just a simple irritation like a cough from a cold.
    • Cough suppressants can be harmful: Many over-the-counter (OTC) cough medicines contain cough suppressants (like dextromethorphan). These work by quieting the cough reflex. For asthma patients, coughing is often a way their body tries to clear mucus and irritants from their narrowed airways. Suppressing this cough can trap mucus and worsen breathing difficulties, potentially leading to more severe asthma attacks.
    • Expectorants have limited evidence for asthma: While expectorants like guaifenesin are designed to thin mucus and make coughs more productive, their effectiveness specifically for asthma-related coughs is not strongly supported by research. In some cases, they might be included in combination medications, but they are not the primary treatment for asthma.
    • Masking symptoms: Using OTC cough medicine can mask the true severity of an asthma flare-up, delaying proper and effective asthma treatment. This can be dangerous, as asthma can rapidly worsen.
    • The real solution is asthma medication: The most effective way to treat a cough in an asthma patient is to address the underlying asthma. This involves:
      • Bronchodilators: These medications (like albuterol, often found in “rescue inhalers”) quickly open up the airways and provide rapid relief from coughing, wheezing, and shortness of breath.
      • Corticosteroids (inhaled or oral): These reduce the inflammation in the airways that causes asthma symptoms, including chronic cough.
      • Other controller medications: These include long-acting bronchodilators, leukotriene modifiers, and biologics, which are used for long-term asthma control and prevention of symptoms.
    • Cough-Variant Asthma (CVA): There is a specific type of asthma called cough-variant asthma where a chronic cough is the only symptom. Even in these cases, standard asthma medications (like inhaled corticosteroids and bronchodilators) are the effective treatment, not OTC cough syrups.

    In summary: If an asthma patient has a cough, they should consult their healthcare provider rather than self-medicating with general cough medicines. The cough is a signal that their asthma may not be well-controlled, and they need appropriate asthma treatment.

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Ali1234Researcher

When is a stem cell transplant necessary?

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  1. Ali1234 Researcher
    Added an answer on July 2, 2025 at 11:35 pm

    A stem cell transplant (also known as a bone marrow transplant) is a complex medical procedure that replaces damaged or diseased blood-forming stem cells with healthy ones. It's considered necessary in situations where a person's bone marrow is not functioning properly, or has been damaged by diseasRead more

    A stem cell transplant (also known as a bone marrow transplant) is a complex medical procedure that replaces damaged or diseased blood-forming stem cells with healthy ones. It’s considered necessary in situations where a person’s bone marrow is not functioning properly, or has been damaged by disease or intense medical treatments.

    Here are the primary situations when a stem cell transplant may be necessary:

    1. Cancers of the Blood and Bone Marrow:

    • Leukemia: Cancers affecting white blood cells where abnormal cells crowd out healthy blood cells.
    • Lymphoma (Hodgkin and Non-Hodgkin): Cancers of the lymphatic system.
    • Multiple Myeloma: A cancer of plasma cells in the bone marrow.
    • Myelodysplastic Syndromes (MDS): Conditions where the bone marrow doesn’t produce enough healthy blood cells, and some types can progress to acute leukemia.
    • Other Blood Disorders: Such as Myelofibrosis, Essential Thrombocytosis, and Polycythemia Vera, when they progress or become resistant to other treatments.

    In these cases, high-dose chemotherapy and/or radiation therapy are often used to kill the cancer cells. However, these treatments also destroy healthy stem cells in the bone marrow. The transplant then “rescues” the patient by replacing these destroyed stem cells, allowing the body to produce healthy new blood cells. In some instances, especially with allogeneic (donor) transplants, the new immune cells from the donor can also directly attack remaining cancer cells (known as the “graft-versus-tumor” or “graft-versus-leukemia” effect).

    2. Non-Cancerous Blood and Immune System Disorders:

    • Aplastic Anemia: A condition where the bone marrow stops producing enough new blood cells of all types.
    • Sickle Cell Disease and Thalassemia: Inherited blood disorders affecting red blood cells.
    • Severe Combined Immunodeficiency (SCID): A group of rare disorders caused by a dysfunctional immune system (often called “bubble boy syndrome”).
    • Inherited Metabolic Diseases: Such as Hurler syndrome, Adrenoleukodystrophy, and Metachromatic Leukodystrophy, where a missing or malfunctioning gene leads to severe defects.
    • Other Immune Disorders: Like Wiskott-Aldrich syndrome.
    • Autoimmune Diseases: In some severe cases that don’t respond to other treatments, such as systemic lupus erythematosus, systemic sclerosis, and multiple sclerosis, although this is a less common indication and often still under investigation.

    Key Considerations for a Stem Cell Transplant:

    • Type of Transplant:
      • Autologous: Uses the patient’s own stem cells, collected before high-dose treatment.
      • Allogeneic: Uses stem cells from a donor (related or unrelated) who has a good tissue match.
      • Syngeneic: Uses stem cells from an identical twin.
    • Patient’s Overall Health: Age, general health, and other medical conditions are crucial factors in determining if a patient can tolerate the intensive treatment and recovery.
    • Disease Status: Whether the disease is in remission, has relapsed, or how sensitive it is to chemotherapy.
    • Availability of a Donor: Especially critical for allogeneic transplants where a suitable match is needed.
    • Potential Benefits vs. Risks: Stem cell transplants carry significant risks and potential complications, so the decision is made carefully, weighing the potential for cure or long-term survival against these risks.

    A stem cell transplant is a major medical undertaking, and the decision to proceed is always made by a team of specialists after a thorough evaluation of the patient’s condition and individual circumstances.

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Ali1234Researcher

کیا پی ٹی آئی حکومت گرائی جا رہی ہے؟

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  1. Ali1234 Researcher
    Added an answer on July 2, 2025 at 11:33 pm

    خیبر پختونخوا میں پی ٹی آئی کی حکومت گرانے اور نہ گرانے کی بحث ملکی سیاسی حلقوں میں زور و شور سے جاری ہے، ایک جانب اہم حکومتی ملاقاتیں جاری ہیں جب کہ دوسری طرف وزیراعلیٰ کے پی نے اس حوالے سے چیلنج بھی دیا ہے۔ وزیراعظم کے مشیر برائے سیاسی امور رانا ثنا اللہ نے واضح کیا ہے کہ خیبرپختونخوا میں پاکستانRead more

    خیبر پختونخوا میں پی ٹی آئی کی حکومت گرانے اور نہ گرانے کی بحث ملکی سیاسی حلقوں میں زور و شور سے جاری ہے، ایک جانب اہم حکومتی ملاقاتیں جاری ہیں جب کہ دوسری طرف وزیراعلیٰ کے پی نے اس حوالے سے چیلنج بھی دیا ہے۔

    وزیراعظم کے مشیر برائے سیاسی امور رانا ثنا اللہ نے واضح کیا ہے کہ خیبرپختونخوا میں پاکستان تحریک انصاف (پی ٹی آئی) کی صوبائی حکومت کے خلاف کسی قسم کی تحریک عدم اعتماد زیر غور نہیں اور نہ ہی مولانا فضل الرحمان سے حکومت گرانے کے حوالے سے کوئی بات کی گئی ہے۔

    یہ خبر بھی پڑھیں: ریاست کو چیلنج کرتا ہوں میری حکومت گرا کر دکھائے تو سیاست چھوڑ دوں گا، وزیراعلیٰ گنڈا پور

    نجی ٹی وی کے پروگرام میں گفتگو کرتے ہوئے رانا ثنا اللہ نے کہا کہ حکومت نے متعدد بار پی ٹی آئی کو مذاکرات کی پیشکش کی، مگر انہوں نے مسلسل انکار کیا۔ پی ٹی آئی کی سیاست ہمیشہ اسٹیبلشمنٹ کے سہارے رہی، وہ اقتدار میں واپس آنے کے لیے ایک بار پھر یہی سہارا چاہتی ہے، مگر اب یہ خواب کبھی پورا نہیں ہوگا۔

    انہوں نے کہا کہ اگر پی ٹی آئی نے اپنی حکومتیں نہ توڑی ہوتیں تو شاید 9 مئی کا سانحہ بھی نہ ہوتا۔ وزیراعظم شہباز شریف نے تو یہاں تک کہا کہ اگر آپ مجھ سے بات نہیں کرنا چاہتے تو اسپیکر چیمبر میں آجائیں، میں وہیں آ جاؤں گا، مگر پی ٹی آئی نے بات چیت کے دروازے بند کیے رکھے۔ پی ٹی آئی جمہوریت کو مکالمے سے نہیں، بلکہ ڈیڈلاک سے چلانا چاہتی ہے۔

    مزید پڑھیں: گنڈا پور کی حکومت گرانے کا ارادہ نہیں، اختیار ولی خان

    رانا ثنا اللہ نے زور دیا کہ خیبرپختونخوا میں پی ٹی آئی کی حکومت اور بانی چیئرمین کی سیاسی امانت کو علی امین گنڈاپور بخوبی سنبھالے ہوئے ہیں۔ اگر پی ٹی آئی پرامن احتجاج کرتی ہے اور قانون ہاتھ میں نہیں لیتی، تو یہ ان کا جمہوری حق ہے۔

    دوسری طرف خیبرپختونخوا حکومت کے ممکنہ تختہ الٹنے کی خبروں کے دوران میں وزیراعظم شہباز شریف سے گورنر کے پی فیصل کریم کنڈی اور عوامی نیشنل پارٹی کے سربراہ ایمل ولی خان نے اہم ملاقاتیں کی ہیں۔

    یہ بھی پڑھیں: وزیراعظم سے گورنر خیبرپختونخوا کی اہم ملاقات، سانحہ سوات پر بریفنگ دی

    گورنر کے پی فیصل کریم کنڈی نے ملاقات کے بعد بتایا کہ اگر اپوزیشن کے پاس اکثریت ہو تو حکومت کی تبدیلی آئینی حق ہے، اسے سازش کہنا درست نہیں۔ انہوں نے واضح کیا کہ مخصوص نشستوں کی بحالی کے بعد بننے والی نئی سیاسی صورتحال پر بھی بات ہوئی اور کہا کہ گنڈاپور کے خلاف سازش کرنے کے لیے ان کے اپنے لوگ ہی کافی ہیں۔

    علاوہ ازیں وزیراعظم کی ایمل ولی خان سے ہونے والی ملاقات میں بھی ملکی سیاسی صورتحال پر تفصیلی بات چیت ہوئی، جس میں مختلف وفاقی وزرا اور معاونین خصوصی بھی شریک تھے۔

    یہ خبر بھی پڑھیں: خیبرپختونخوا سے قومی اور صوبائی اسمبلی کیلیے خواتین و اقلیتی نشستوں پر کامیاب امیدواروں کے ناموں کا اعلان

    دریں اثنا جے یو آئی (ف) کے سربراہ مولانا فضل الرحمان نے بھی خیبرپختونخوا حکومت کے خلاف کسی ممکنہ تحریک عدم اعتماد سے علیحدگی اختیار کر لی ہے۔ ذرائع کے حوالے سے نجی ٹی وی کی رپورٹ کے مطابق مولانا فضل الرحمٰن کا پیغام اڈیالہ جیل میں بانی چیئرمین پی ٹی آئی تک پہنچا دیا گیا ہے، جو ان کی بہنوں کے ذریعے جیل ملاقات کے دوران دیا گیا۔ پیغام میں مؤقف اختیار کیا گیا کہ حکومت گرانے کے لیے مولانا سے رابطہ کیا گیا تھا مگر انہوں نے انکار کر دیا۔

    اسی سیاسی تناظر میں وزیراعلیٰ خیبرپختونخوا علی امین گنڈاپور کا جارحانہ ردعمل بھی سامنے آیا ہے۔ انہوں نے دو ٹوک الفاظ میں کہا ہے کہ چاہے جتنا زور لگا لیا جائے، آئینی طریقے سے ان کی حکومت کو نہیں گرایا جا سکتا۔ انہوں نے چیلنج کرتے ہوئے کہا کہ اگر ان کی حکومت گرائی گئی تو وہ سیاست ہی چھوڑ دیں گے۔

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Ali1234Researcher

How did Amir Khan's marriage get ruined by Miandad's six?

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  1. Ali1234 Researcher
    Added an answer on July 2, 2025 at 2:05 pm

    Aamir Khan's first marriage to Reena Dutta, which was a secret wedding due to family disapproval, coincided with a famous India-Pakistan cricket match on April 10, 1986, in Sharjah. While Aamir and Reena had secretly tied the knot, their families were engrossed in watching the cricket match, so no oRead more

    Aamir Khan’s first marriage to Reena Dutta, which was a secret wedding due to family disapproval, coincided with a famous India-Pakistan cricket match on April 10, 1986, in Sharjah.
    While Aamir and Reena had secretly tied the knot, their families were engrossed in watching the cricket match, so no one noticed their absence. Aamir was thrilled because India was winning, hoping his wedding day would be remembered with an Indian victory.
    However, in a dramatic turn of events, Javed Miandad hit a six off the last ball, leading to India’s defeat. This moment caused immense disappointment for Indian fans, and for Aamir Khan, it “ruined” his wedding day by turning his joy into profound upset and even “depression” because of India’s loss.
    Years later, when Aamir Khan met Javed Miandad on a flight, he jokingly told him, “Javed Bhai, you didn’t do right to me! You ruined my wedding because you hit that six on the last ball, and I was terribly disappointed.” This highlights how the significant sporting moment overshadowed his personal milestone for him.

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Ali1234Researcher

شیفالی کی موت سے اینٹی ایجنگ انجیکشن کا تعلق؟

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Ali1234Researcher
In: Election, Pakistan

Pakistan Election Commission decision; How many reserved seats of which party were restored?

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  1. Ali1234 Researcher
    Added an answer on July 2, 2025 at 2:01 pm

    The Election Commission of Pakistan (ECP) has not restored reserved seats to the Pakistan Tehreek-e-Insaf (PTI) or its allied party, the Sunni Ittehad Council (SIC). Instead, following a Supreme Court verdict, the ECP has distributed the reserved seats previously earmarked for the PTI/SIC to other pRead more

    The Election Commission of Pakistan (ECP) has not restored reserved seats to the Pakistan Tehreek-e-Insaf (PTI) or its allied party, the Sunni Ittehad Council (SIC). Instead, following a Supreme Court verdict, the ECP has distributed the reserved seats previously earmarked for the PTI/SIC to other political parties, primarily the ruling coalition.
    Here’s a breakdown of the recent developments:
    * Supreme Court’s Verdict (June 27, 2025): A 7-3 majority ruling by a Constitutional Bench of the Supreme Court overturned its own previous judgment (July 12, 2024) that had declared the PTI eligible for reserved seats. This new decision effectively stated that the PTI (or the SIC, which PTI-backed independents joined) was not entitled to reserved seats because of “non-curable legal defects and violation of a mandatory provision of submission of party list for reserved seats.” This decision essentially meant PTI was no longer considered a parliamentary party for the purpose of reserved seats.
    * ECP’s Decision (July 2, 2025): Following the Supreme Court’s verdict, the ECP proceeded to distribute the 77 reserved seats (for women and non-Muslims) in the National Assembly and provincial assemblies that were previously claimed by the SIC/PTI.
    * Distribution of Seats (National Assembly): According to legal experts, of the 22 reserved seats in the National Assembly, the distribution is as follows:
    * Pakistan Muslim League-Nawaz (PML-N): 15 seats
    * Pakistan Peoples Party (PPP): 4 seats
    * Jamiat Ulema-e-Islam (JUI-F): 3 seats
    * Distribution of Seats (Provincial Assemblies):
    * Khyber Pakhtunkhwa Assembly: 10 seats to JUI-F, 7 to PML-N, 6 to PPP, and one each to PTI-Parliamentarians and Awami National Party.
    This redistribution of reserved seats has significantly strengthened the ruling coalition, allowing them to achieve a two-thirds majority in the National Assembly.

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Ali1234Researcher

دوسرے بینک کے اے ٹی ایم سے رقم نکلوانے پر چارجز میں اضافہ ہوگیا

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  1. Ali1234 Researcher
    Added an answer on July 2, 2025 at 1:59 pm

    ملک بھر کے کمرشل بینکوں نے دوسرے بینک کے اے ٹی ایم سے رقم نکلوانے پر چارجز میں اضافہ کر دیا۔ اپنے بینک کے علاوہ دوسرے بینک کے اے ٹی ایم سے رقم نکلوانے پر اب 23 روپے 44 پیسے سے 25 روپے کے چارجز دینے ہوں گے۔ یکم جولائی سے اے ٹی ایم ٹرانزیکشنز پر نئے چارجز اور قوائد نافذ العمل ہو گئے۔ اپنے بینک کی برانRead more

    ملک بھر کے کمرشل بینکوں نے دوسرے بینک کے اے ٹی ایم سے رقم نکلوانے پر چارجز میں اضافہ کر دیا۔
    اپنے بینک کے علاوہ دوسرے بینک کے اے ٹی ایم سے رقم نکلوانے پر اب 23 روپے 44 پیسے سے 25 روپے کے چارجز دینے ہوں گے۔
    یکم جولائی سے اے ٹی ایم ٹرانزیکشنز پر نئے چارجز اور قوائد نافذ العمل ہو گئے۔
    اپنے بینک کی برانچز کے اے ٹی ایم سے رقم نکلوانے پر کوئی چارجز نہیں ہوں گے۔
    بین الاقوامی اے ٹی ایم سے رقم نکالنے پر 2 فیصد سے 8 فیصد یا 300 روپے سے 1000 روپے تک فیس لاگو ہو گی جو بینک کے لحاظ سے مختلف ہوسکتی ہے۔

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